Lenora Epple, DO, MBA

Dr. Lenora Epple is an Internal Medicine physician in Jefferson City, Missouri focused on adults who want thoughtful, personalized primary care, including preventive visits, chronic condition management, medication review, lab evaluation, hormone and metabolic health, and long-term wellness planning.

Dr. Epple graduated from Kansas City University of Medicine and Biosciences and completed her Internal Medicine residency at the University of Missouri. She is a clinician, educator, writer, and speaker with expertise in Preventive Medicine, Lifestyle Medicine, and Wellness.

Known for her collaborative approach, Dr. Epple partners closely with each patient to create personalized goals and treatment plans that fit their unique lives. Her care philosophy blends the science of medicine with the art of listening — helping patients understand their bodies, take active roles in their care, and build lasting habits that support lifelong health.

Her clinical interests include longevity, hormone balance, cardiovascular and cancer prevention, metabolic health (including prediabetes, diabetes, and weight management), and food sensitivities. She also focuses on thyroid and brain health — supporting cognitive function, emotional wellbeing, and sleep quality.

She has a special interest in plant-based nutrition for disease prevention and is pursuing certification in Culinary Medicine. Dr. Epple is a proud member of the American Medical Association, the American College of Physicians, The Menopause Society, the American College of Lifestyle Medicine, and the International Society for the Study of Women's Sexual Health.